Journal of Osh State University. Medicine
Journal of Osh State University. Medicine
e-ISSN 1694-8831
DOI: 10.52754/16948831
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Dynamics of chronic viral hepatitis B and vaccination coverage of the population in Osh region

Kanykei Kalybekova, Zuridin Nurmatov, Begimai Abdimomunova, Aizharkyn Akzholtoeva

Abstract

This study aimed to investigate long‑term epidemiological trends of viral hepatitis B in the Kyrgyz Republic and Osh region, assessing the role of population vaccination coverage. The study materials included data from state statistical reports, information databases of sanitary‑epidemiological surveillance authorities, and official reports of medical‑preventive institutions for the period 2014‑2024. The work employed methods of retrospective epidemiological analysis, comparative assessment of morbidity rates, territorial distribution of cases, and comparison of vaccination coverage levels. The results showed that the long‑term dynamics of viral hepatitis B incidence exhibit pronounced fluctuations: the highest total incidence rates were recorded in 2016 (14,615 cases), while the lowest were in 2021 (2,090 cases). During the COVID‑19 pandemic, case detection declined, after which a marked increase has been observed since 2022, reaching 18,081 cases in 2024 – a rise associated with the restoration of diagnostic volumes and strengthened epidemiological surveillance. In Osh region, a substantial increase in registered chronic viral hepatitis B cases was found: from 519 cases in 2022 to 2,289 cases in 2023, with a persistently high level in 2024 (2,148 cases). Marked territorial heterogeneity of morbidity was identified: in 2023, the highest rates were recorded in Kara‑Suu district (652 cases), Osh city (419), Uzgen district (420) and Aravan district (308). In 2024, incidence rates remained high in the same territories, reaching 611 cases in Kara‑Suu district, 373 in Osh city, 308 in Uzgen district and 324 in Aravan district. It was established that, despite the overall supply of vaccines to the region amounting to 274,550 doses, a significant remainder persists (98,178 doses), including in Kara‑Suu district (30,883 doses) and Uzgen district (20,335 doses). This indicates insufficient coverage of preventive immunisation, especially in areas with a high epidemiological burden


Keywords:

population; immunisation; morbidity dynamics; vaccination coverage; immunoprophylaxis; epidemiological dynamics; epidemiological surveillance

https://doi.org/10.52754/16948645_2026_5(1)_08

Retrieved from Vol. 5, No. 1, 2026

Pages 8-16

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Suggested citation

APA
Kalybekova, K., Nurmatov, Z., Abdimomunova, B., & Akzholtoeva, A. (2026). Dynamics of chronic viral hepatitis B and vaccination coverage of the population in Osh region. Journal of Osh State University. Medicine, 5(1), 8-16. https://doi.org/10.52754/16948645_2026_5(1)_08
Vancouver
Kalybekova K, Nurmatov Z, Abdimomunova B, Akzholtoeva A. Dynamics of chronic viral hepatitis B and vaccination coverage of the population in Osh region. J Osh State Univ Med. 2026;5(1):8–16. doi:10.52754/16948645_2026_5(1)_08