Received 05.03.2025, Revised 19.05.2025, Accepted 16.06.2025
The purpose of this study was to identify neuropsychological features and the degree of functional autonomy in patients with ischaemic stroke in the late recovery period. The methodology was based on a cohort comparative study of 142 patients aged 50-80 years, conducted with the participation of the Kyrgyz State Medical Institute of Postgraduate Education and the Amanat University Clinic as a clinical base using scales to assess cognitive function, depression, anxiety, and functional autonomy questionnaire. The principal findings of the study demonstrated a high prevalence of neuropsychological disorders in patients in the late recovery period of ischaemic stroke. Cognitive deficits persisted in 82.7% of the patients, with an average score of 21.1 points on the cognitive function assessment scale. Short-term memory (68.4%), attention (60.2%), and orientation (46.9%) impairments were the most pronounced. Affective disorders were found in 72.4% of the participants, with major depression in 9.2% and severe depression in 28.5%; the mean depression scale score was 19.6 points. The level of anxiety exceeded the clinical threshold in 63.2% of patients, with a mean score on the Hamilton anxiety scale of 21.3. The mean score of functional autonomy in the experimental group was 13.8 points, and in patients with severe depression it decreased to 10.3. Women showed more pronounced affective symptoms and a lower level of autonomy than men. In the age subgroup over 70 years of age, a trend towards more pronounced cognitive decline and increased affective impairment was observed compared to other age categories. Cognitive-affective disorders detected in most patients had systemic impact on everyday autonomy and require complex correction already in the posthospital period. The findings are of practical value for neurologists, psychiatrists, and rehabilitation specialists, as they can be used in the development of individualised programmes of neuropsychological support for patients in the late post-stroke period
neuropsychological disorders; functional autonomy; depression; cognitive function; anxiety; memory; attention